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multiphoton microscopy mpm  (Oxford Instruments)


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    Oxford Instruments multiphoton microscopy mpm
    Multiphoton Microscopy Mpm, supplied by Oxford Instruments, used in various techniques. Bioz Stars score: 99/100, based on 44410 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/multiphoton+microscopy+mpm/Imaris/pm36766797-9-3-6
    Average 99 stars, based on 44410 article reviews
    multiphoton microscopy mpm - by Bioz Stars, 2026-10
    99/100 stars

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    Microscopy:

    Article Title: IL18 Receptor Signaling Inhibits Intratumoral CD8 + T-Cell Migration in a Murine Pancreatic Cancer Model
    Article Snippet: .. After visualization with multiphoton microscopy (MPM), Imaris software was used to perform T-cell tracking. .. Imaris analysis indicates a significantly higher accumulation of Il18r −/− CTLs in PancOVA tumors and a significant reduction in tumor volume compared to wild-type CTLs.



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    Graphical abstract of experimental design for imaging intravital C’Dot uptake and clearance in bone with 2-photon microscopy. A) Bone and osteocytes were exposed to fluorescent nanoparticles through a local subcutaneous injection above the third metatarsal (MT3) bone in a mouse hind paw. After C’Dot incubation, the MT3 was surgically isolated and secured for multiphoton imaging. B-D) Example images of C’Dots in the lacuno-canalicular network are shown. E-F) The high resolution of our imaging system enables subcellular localization. G) A short C’Dot incubation time and high frame averaging allows visualization of the canalicular network. H) Images can be analyzed for clearance kinetics of nanoparticle signal (from previous paper ) as well as subcellular distribution of signal. Scale bars = 10 μm.

    Journal: Scientific Reports

    Article Title: Real-time visualization and modulation of endocytic dynamics in osteocytes in vivo

    doi: 10.1038/s41598-025-05735-1

    Figure Lengend Snippet: Graphical abstract of experimental design for imaging intravital C’Dot uptake and clearance in bone with 2-photon microscopy. A) Bone and osteocytes were exposed to fluorescent nanoparticles through a local subcutaneous injection above the third metatarsal (MT3) bone in a mouse hind paw. After C’Dot incubation, the MT3 was surgically isolated and secured for multiphoton imaging. B-D) Example images of C’Dots in the lacuno-canalicular network are shown. E-F) The high resolution of our imaging system enables subcellular localization. G) A short C’Dot incubation time and high frame averaging allows visualization of the canalicular network. H) Images can be analyzed for clearance kinetics of nanoparticle signal (from previous paper ) as well as subcellular distribution of signal. Scale bars = 10 μm.

    Article Snippet: Fluorescent signal inside the functionally isolated MT3 was visualized with multiphoton microscopy (MPM) (Bergamo II, Thorlabs) as previously described .

    Techniques: Imaging, Microscopy, Injection, Incubation, Isolation